Easy: redefine "def" from within a 'use form (possibly using kennytilton's faux special globals) such that it keeps a table of defined functions (which is what you intend to do anyway). Replace all locals with (uniq)'ed names (in case someone uses uses a function name as a local - (def foo () nil) (def bar (foo) (foo))) ). Then for each expression in the file, replace all symbols (outside of quote-forms) that match a key in the table to references to the table itself.
The hard part is the replacing of local variables with (uniq)'ed symbols. But I think local variables should be replaced anyway, because otherwise macros will override local variables with the same name.
